Mark is also the scriptwriter of the film, which starts shooting March 31 in New York and Rome.
The film will feature Kristen Bell in the role of a success-based Gotham real estate agent who can not find a lasting relationship, says Variety magazine.
The woman took off for marriage after her younger sister marries impulsively in Rome.
Meanwhile, she collects coins from a reputation "fountain of love", leading to an overabundance of contenders awaiting his return home.
Kristen Bell, who was part of the 'Heroes' cast of this last season, will now be seen playing the title role in the comedy "Forgetting Sarah Marshall," produced and written by Judd Apatow for Universal.
She will also appear in "Fanboys" for the Weinstein Co.